1、粘菌素在鮑曼不動桿菌感染粘菌素在鮑曼不動桿菌感染VAP中的治療效果中的治療效果 陳陳 延延 杰杰 2013.7.421俞云松.多藥耐藥鮑曼不動桿菌21世紀革蘭陰性茵的“MRSA”J.中華臨床感染病雜志,2009,2(2):65-68. 多藥耐藥多藥耐藥MDRAB、全耐藥、全耐藥PDRAB、廣泛耐藥、廣泛耐藥XDRAB2施毅.正確應對不動桿菌肺部感染J.中國呼吸與危重監護雜志,2012,11(1):13-14.3中國鮑曼不動桿菌感染診治與防控專家共識,中華醫學雜志,2012,92(2);76-85.Literature 14F imek, H Gedik, MT Yldrmak,et al. C

2、olistin against colistin-only-susceptible Acinetobacter baumannii-related infections: Monotherapy or combination therapy?J. Indian Journal of Medical Microbiology, 2012, 30(4): 448-52.VAPClinical responseP=0.821Microbiological responseP=0.113Literature 25 H.AYDEMIR1, D. AKDUMAN,N.PISKIN,et al. Colis

3、tin vs. the combination of colistin and rifampicin for thetreatment of carbapenem-resistant Acinetobacter baumannii ventilator-associated pneumoniaJ. Epidemiol. Infect, 2012:1-9.43名患者在治療期間，有名患者在治療期間，有10名患者（名患者（23%）出現了腎毒性。）出現了腎毒性。Literature 36 Qin Lu, M.D., Ph.D., Rubin Luo M.D., Liliane Bodin, M.D.,

4、et al. Efficacy of High-dose Nebulized Colistin in Ventilator-associated Pneumonia Caused by Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumanniiJ. Anesthesiology ,2012,117(6):1335-47 .500iu常規用量常規用量200-400iucolistin monotherapycolistin combinationClinical cure67%68%Summary1俞云松俞云松.多

5、藥耐藥鮑曼不動桿菌多藥耐藥鮑曼不動桿菌21世紀革蘭陰性茵的世紀革蘭陰性茵的“MRSA”J.中華臨床感染中華臨床感染病雜志病雜志,2009,2(2):65-68.2施毅施毅.正確應對不動桿菌肺部感染正確應對不動桿菌肺部感染J.中國呼吸與危重監護志中國呼吸與危重監護志,2012,11(1):13-14.3中國鮑曼不動桿菌感染診治與防控專家共識中國鮑曼不動桿菌感染診治與防控專家共識,中華醫學雜志，中華醫學雜志，2012,92(2):76-85.4F imek, H Gedik, MT Yldrmak,et al. Colistin against colistin-only-susceptible

6、Acinetobacter baumannii-related infections: Monotherapy or combination therapy?J. Indian Journal of Medical Microbiology, 2012, 30(4): 448-452.5 H.AYDEMIR1, D. AKDUMAN,N.PISKIN,et al. Colistin vs. the combination of colistin and rifampicin for thetreatment of carbapenem-resistant Acinetobacter baumannii ventilator-associated pneumoniaJ. Epidemiol. Infect, 2012:1-9.6 Qin Lu, M.D., Ph.D., Rubin Luo M.D., Liliane Bodin, M.D.,et al. Efficacy of High-dose Nebulized Colistin in Ventilator-associated Pneumonia Caused by Mult