Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMPPhydrochlorideCat.No.:HY-103454B分?式:C??H??ClN?O?分?量:506.04作?靶點:EstrogenReceptor/ERR;Apoptosis作?通路:Others;Apoptosis儲存?式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性數據體外實驗DMSO:250mg/mL(494.03mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲備液1mM1.9761mL9.8806mL19.7613mL5mM0.3952mL1.9761mL3.9523mL10mM0.1976mL0.9881mL1.9761mL體內實驗請根據您的實驗動物和給藥?式選擇適當的溶解?案。以下溶解?案都請先按照InVitro?式配制澄的儲備液，再依次添加助溶劑：(為保證實驗結果的可靠性，澄的儲備液可以根據儲存條件，適當保存；體內實驗的?作液，建議您現?現配，當天使?；以下溶劑前顯?的百分?指該溶劑在您配制終溶液中的體積占?；如在配制過程中出現沉淀、析出現象，可以通過加熱和/或超聲的?式助溶)1.請依序添加每種溶劑：10%DMSO>>40%PEG300>>5%Tween-80>>45%salineSolubility:≥2.08mg/mL(4.11mM);Clearsolution2.請依序添加每種溶劑：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.08mg/mL(4.11mM);Clearsolution3.請依序添加每種溶劑：10%DMSO>>90%cornoilSolubility:≥2.08mg/mL(4.11mM);Clearsolution1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEBIOLOGICALACTIVITY?物活性MPPhydrochloride?種強效的選擇性ER(雌激素受體)調節劑。MPPhydrochloride可誘導?宮內膜癌和oLE細胞凋亡。MPPhydrochloride可逆轉β-雌激素的積極作?。在體內，MPPhydrochloride對???宮ERalpha具有激動劑和拮抗劑的混合作?。IC50&TargetERαERβ戶使?本產品發表的科研?獻?Phytomedicine.27February2022,154022.?MolNutrFoodRes.2021Jul5;e2100070.?MetabBrainDis.2022Jul2.?EurJInflamm.October11,2021.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].DavisAM,etal.Theeffectsoftheselectiveestrogenreceptormodulators,methyl-piperidino-pyrazole(MPP),andraloxifeneinnormalandcancerousendometrialcelllinesandinthemurineuterus.MolReprodDev.2006Aug;73(8):1034-44.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792