ConstructiveCaseNumber:ZM111711Customer:Dr.Manuscripttitle:脾切除加斷流術門脈高壓癥兔腸微生態狀況及微生態制劑的預研GeneralGeneralSummaryofThisThisstudyinvestigatedtheeffectsofmicrobialagentsonportalhypertensionmodelrabbitaftersplenectomywithdevascularization.Theauthorsused35rabbitsandsplitthemintogroups.And18post-operationsurvivorswerestudied.Accordingtotheauthors,microbialagentswerebeneficialtothepost-operationrabbits.First,thenumberofsurvivorrabbitsislimited,especiallyafterregrou.Thesignificanceofstatisticalysisbasedonthisnumberisnotveryconvincing.Second,thewaytheauthorsdidstatisticalysisrequiresimprovement.Isuggestthattheyshouldfindprofessionalassistance.這項研究探討了微生態制劑對脾切除加賁門周圍血管離斷門脈高壓兔模3518NoveltyandClinicalThenoveltyofthisstudyisgood,sincetherearenotalotsimilarreportsbeingpublishedrecently.Portalhypertensioniscommonlyseeninpatientswithliverdiseases.Thereforethedatainthismanuscriptmaybeusefulforthisgroupofpatients.Butthisstudyisbasedonrabbitmodel.Humanexperimentsarestillneededtovalidatetheresultshere.GrammarandEnglishTheentiremanuscriptisinChinese.AtleasttheauthorsneedtotranslatetheintoEnglish.整篇文章都是中文。作者至少需要將翻譯成英文Thiswillbeamajorjob.Alotofproblemswereobservedinthismanuscript.Manyoftheseproblemsmaydirectlyleadtorejection.MissingSeeotherOthersignificantcommentsareSpecificSpecificTitleThetitle脾切除加斷流術門脈高壓癥兔腸微生態狀況及微生態制劑的干預研究”generallyadequayconveysthecontentofthepaper.Thismanuscriptisabouttheeffectsofmicrobialagents,notthestatusofmicrobialsinrabbitmodel.Thereforethefirstpartofthistitleshouldberemoved.標題“脾切除加斷流術門脈高壓癥兔腸微生態狀況及微生態制劑的干預研究”大模型的腸微生態狀況。因此這個標題的前一部分可以刪除。“微生態制劑”Thisshouldbemorespecific,sinceitseemsthereisonlyoneagentinvolvedinthisstudy.“微生態制劑”Themanuscriptdidnotcomewithatitlepage,whichmustincludethetitle,runningtitle,andthedetailedauthorinformation.息未給國外編輯&ThissectionneedssignificantItshouldbetranslatedintoEnglish.EvenChinesejournalsrequirean.應將其翻譯成英語。即使中文期也要求要有一個英要 istoolong.Mostjournalsrequire oflessthan250這個過長。大多數期要求要少于250個字“①微生態制劑組（MOG：10只、②葡萄糖對照組(GOG：8只)分別灌服乳果糖+雙歧桿菌活菌、葡萄糖”Hereitisconfusing.Descriptionofeachgroupshouldberightafterthenameofthegroup.“①微生態制劑組（MOG：10只、②葡萄糖對照組(GOG：8只)分別灌服乳果糖+雙歧桿菌活菌、葡萄糖”這里有點。對每組的說明應該放在該組名“5只僅作為模型對照Idon’tseeanydataonthisgroupArethese5rabbitsintheoriginal35,ornot?“5只僅作為模型對照”355只么，還是不包括 :Thereare5 whicharerelatedtothetopicofthepresentstudy.“微生態制劑”aspecificnameshouldbeprovided.：這里有5個，均與本研究的相關。“微生態制劑”應提TheIntroductionispoorlywrittenandneedssignificantrevision.Itisveryshortandbrief.Thekeyconceptsandtechniquesinvolvedinthisstudyshouldallbeintroducedhere.Theauthorsfailedtodoso.這項涉及的主要概念及技術都應該在這里加以介紹作者沒有這樣做Statementsmadeinthissectionshouldbesupportedbyproper在這一節的敘述應適當的文獻加以支持Theauthorsshouldtryhardertostressoutwhythisstudyisimportantandclinicallysignificant.ThisisoneofthemostimportantelementsforagoodIntroduction.作者應盡量強調這項研究之所以很重要的原因及其臨床意義。這是一個較好的引言的最重要的元一。MaterialsandThissectionneedssignificantrevisionbefore“ShamOperationGroupWhathavebeendoneinthisgroup?Therearetoomanydeathcasesinthisstudy.Idon’tthinkthisisnormalforthisoperation.Thisshouldbeexplained.在這項研究中的案例太多了。我認為這不是這種手術的正常情況。對此“以二次法血吸蟲尾蚴建立門脈高壓癥動物模型行血流動力學檢查驗證模型。”Moredetailsonthismodelandwhatprotocoltheauthorsfollowedshouldbeprovided,aswellastheprotocolonhowthemodelwastested.Ifthishasbeendonepreviouslyinthislabandpublishedalreadyareferenceshouldbelisted.“以二次法血吸蟲尾蚴建立門脈高壓癥動物模型行血流動力學檢查驗證模型”關于這一模型的的細節信息及作者所遵循的方案以及如何測試模型的方案應予以提供。如果這在本先前已經完成且已經，應“5只兔僅作為模型對照。Wheredidthis5rabbitscomefrom?Theymustcomefromthesamesourceasthestudygroupsothattheycouldbeusedascontrol“5只兔僅作為模型對照。”5只兔出自哪里？它們必須與研究組的來Allreagents/medications/equipmentsshouldbeintroducedwithspecificdetails,whichincludethemodel,resource,dosage,andetc.Forexample,“送超微病理電鏡下觀察腸黏膜病變”,heretheinformationupontheEMshouldbeprovided.例如“送超微病理電鏡下觀察腸黏膜病變”,EM“總膽紅素（TBLL）Itshouldbe“TBIL”.AbbreviationssuchasTEandITSshouldbeTEITSIn1.3.5,圖像分析系統”needsmore在1.3.5節“圖像分析系統”需要有的說明The ysisisTheResultssectionistoosimpleandmoredescriptionshouldbe結果部分過于簡單，應提供的說明Theauthorsshouldbrieflyexplainwhytheywanttodoeachexperimentatthebeginningofeachparagraph,andwhatthesignificanceofeachgroupofdataattheend.Thiswillmaketheentiremanuscriptmorelikealogicstory.Theauthorsshouldgivemoredescriptionsintextonfiguresanddata,insteadofjustonesentenceineachparagraph.關于圖和數據作者應給出的文字說明而不是每段中只有一句話描述Figuresshouldbenumberedas“Figure1”andetc,not“FigureA,B,C,Dshouldbemergedintoone,asarefigureE,F,G,A、B、C、DE、F、G、HThefigurelegendsarethere,butfailtomeettherequirementsofSCIfigurelegends.Thelegendsshouldbedescriptivewithoutanyfurtherysis.Nocomparisonshouldbeinthelegends.SCIIntable1,thereis“抽樣模型組”.Nopreviousdefinitionofthistermhasbeenprovided.Itneedsexplanation.1中，有“抽樣模型組”。前文并沒有提供這一詞語的定義。需要解釋一FiguresshouldputinappropriateformatsforSCI圖應根據SCI期的要求，用合適的格式呈現“vsGOG、SOG、NOGisatthebottomoftable2.Thisisnotanappropriatewaytopresentstatisticaldata.Comparisonshouldbedonebetween2groupsateverytime,notwith3.“括號內為陽性率”Itseemsitshouldbepercentage,butinthetable,no“%”isused.2底部的“vsGOG、SOG、NOG”。這里呈現統計數據的方式不太合適。23組。“括號內為陽性率”這似乎應該是百分比，Throughoutthemanuscript,微生態制劑wasused.Butactuallythereisonlyoneagent“Bifidobacteriumused.Sothenameofthisagentshouldbeusedinsteadof貫穿全文使用了微生態制劑。但實際上，這里只有一種試劑“2.8腸道菌群DNA圖譜分析”.Theysisdescribedhereisnotveryconvincing.HowmanytimeshavethisDNAgelbeenrepeated?Aretheyallthesame?Inaddition,therearestrongvariationsobservedbetweenL3-10,thestudygroup.Howtoexplainthis,andhowcanyoudrawsuchconclusionfromthisinconsistentdata?Thefirst2paragraphsshouldbeinIntroduction,notThefindingsthatareeitherdifferentfromorconsistentwiththeotherstudiesshouldbediscussed.Theauthorsfailedtodothis.ThisisamajormistakeforwritingagoodDiscussion.Thereisnoparagraphindicatingthelimitationsofthestudy.Theauthorsshouldprovidealistofwhattheybelievethelimitationsare.沒有段落這項研究的局限性。作者應列出他們所認為的局限性有哪些ThereshouldbeoneparagraphattheendoftheDiscussiontoconcludewhattheauthorsfoundintheirstudyTheoneprovidedbytheauthorsisnotconciseenough.無Thereare