1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemENotoginsenoside Ft1Cat. No.: HY-N0910CAS No.: 155683-00-4分式: CHO分量: 917.13作靶點: Others作通路: Others儲存式: 4C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (stored undernitrogen)溶解性數據體外實驗 DMSO : 6.67 mg/mL (7.27 m

2、M; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.0904 mL 5.4518 mL 10.9036 mL5 mM 0.2181 mL 1.0904 mL 2.1807 mL10 mM - - -請根據產品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內實驗 請根據您的實驗動物和給藥式選擇適當的溶解案，配制前請先配制澄清的儲備液，再依次添加助溶劑(為保證實驗結果的可靠性，體內實驗的作液，建議您現現配，當天使；澄清的儲備液可以根據儲存條件，適當保存；以下溶劑前的百分 指

3、該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 0.67 mg/mL (0.73 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 0.67 mg/mL (0.73 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 0.67 mg/mL (0.73 mM); Clear solutio

4、n1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 三七皂苷Ft1(Notoginsenoside Ft1)植物分離三七皂苷，刺激管成。REFERENCES1. Shen K, et al. Notoginsenoside Ft1 promotes angiogenesis via HIF-1 mediated VEGF secretion and the regulation of PI3K/AKT andRaf/MEK/ERK signaling pathways. Biochem Pharmac

5、ol. 2012 Sep 15;84(6):784-92.2. Gao B, et al. Platelet P2Y? receptors are involved in the haemostatic effect of notoginsenoside Ft1, a saponin isolated from Panaxnotoginseng. Br J Pharmacol. 2014 Jan;171(1):214-23.3. Shen K, et al. Notoginsenoside Ft1 activates both glucocorticoid and estrogen recep

6、tors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Biochem Pharmacol. 2014 Mar 1;88(1):66-74.4. Gao B, et al. p38 MAPK and ERK1/2 pathways are involved in the pro-apoptotic effect of notoginsenoside Ft1 on human neuroblastomaSH-SY5Y cells. Life Sci. 2014 Jul 17;108(2):63-70.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 4