POLITICS

&

SOCIETYDepressioninItalyCHAPTER

01GlobaloverviewPercentageofindividualsworldwidereportingmoderatetoseveresymptomsofstress,depression,andanxietyin2022,byagegroupShareofpeopleworldwidewithstress,depression,andanxietyin2022,byageStressDepressionAnxiety70%60%50%40%30%20%10%0%66%64%57%49%38%27%25%24%20%17%12%11%10%8%7%5%3%1%18-2425-3435-4445-5455-6465andolder3Description:Asurveyconductedin2022foundthatyoungadultsagedbetween18and24weremorelikelytosufferfrommoderatetoseverestress,depression,andanxietysymptoms.Thatyear,around66percentofrespondentsfromthisagegroupreportedstress-relatedsymptoms,while25percentofthoseaged65andolderhadsimilarsymptoms.Thisstatisticdisplaysthepercentageofindividualsworldwidereportingmoderatetoseveresymptomsofstress,depression,andanxietyin2022byage[...]

ReadmoreNote(s):Worldwide;September5toOctober5,2022;30,636respondents;18-74years;self-reporteddataSource(s):AXA;IpsosPercentageofrespondentsworldwidewhohavefeltanxietyordepressionformorethantwoweeksasof2020,byregionShareofrespondentsworldwidewhofeltanxietyordepressionasof2020,byregionPercentageofrespondents0%5%10%15%20%25%30%35%LatinAmericaRussia/Caucasus/CentralAsiaAustralia/NewZealandSouthAsia33%27%26%22%22%22%22%MiddleEast/NorthAfricaWesternEuropeNorthernAmericaSub-SaharanAfricaEasternEurope20%20%19%18%WorldSoutheastAsiaEastAsia9%4Description:In2020,around33percentofindividualsinLatinAmericareportedthatatleastonceintheirlifetimetheyweresoanxiousordepressedthattheycouldnotcontinuetheirregulardailyactivitiesastheynormallywouldfortwoweeksorlonger.Thisstatisticillustratesthepercentageofrespondentsworldwidewhoatsomepointintheirlifehadfeltsoanxiousordepressedthattheycouldnotcontinuetheirregulardailyactivitiesastheynormallywouldfortwoweeksorlongerasof2020,by[...]

ReadmoreNote(s):Worldwide;2020;over119,000;15yearsandolder;113countriesSource(s):WellcomeTrustPercentageofrespondentsworldwidewhofeltanxietyordepressionformorethantwoweeksasof2020,bycountryincomeandageRespondentsworldwidewhofeltanxietyordepression2020,bycountryincomeandage15to24years25to34years25to49years50to64years65yearsandolder30%25%20%15%10%5%26%24%24%22%22%21%21%20%

20%20%20%18%18%17%16%14%14%14%14%13%0%AllcountriesLow/Lower-middleincomecountriesUpper-middleincomecountriesHigh-incomecountries5Description:In2020,around26percentofthoseaged25to34yearsinhigh-incomecountriesreportedthatatleastonceintheirlifetimetheyweresoanxiousordepressedthattheycouldnotcontinuetheirregulardailyactivitiesastheynormallywouldfortwoweeksorlonger.Thisstatisticillustratesthepercentageofrespondentsworldwidewhoatsomepointintheirlifehadfeltsoanxiousordepressedthattheycouldnotcontinuetheirregulardailyactivitiesastheynormallywouldfortwoweeksor[...]

ReadmoreNote(s):Worldwide;2020;over119,000;15yearsandolder;113countriesSource(s):WellcomeTrustPercentageofrespondentsworldwidewhofoundselectapproacheshelpfulinalleviatinganxietyordepressionasof2020Reportedhelpfulnessofselectactionsforanxiety/depressionworldwidein2020PercentageofrespondentsVeryhelpful20%Somewhathelpful40%Nothelpful60%0%80%27%28%100%5%120%Spendingtimeinnature/theoutdoorsImprovinghealthylifestylebehaviorsTalkingtofriendsorfamily67%66%6%5%63%60%31%30%Engaginginreligious/spiritualactivitiesTalkingtomentalhealthprofessionalMakingachangetopersonalrelationshipsMakingachangetoworksituationTakingprescribedmedication9%9%59%58%30%32%9%10%11%56%33%35%53%6Description:In2020,around53percentofrespondentsworldwideaged15yearsandolderreportedthattakingprescribedmedicationwasveryhelpfulinalleviatingfeelingsofanxietyordepressionthattheyhad,comparedto11percentofrespondentswhostatedthattakingprescribedmedicationwasnothelpful.Thisstatisticillustratesthereportedhelpfulnessofselectactionsinalleviatinganxietyordepressionaccordingtorespondentsworldwideasof2020.ReadmoreNote(s):Worldwide;2020;over119,000;15yearsandolder;113countriesSource(s):WellcomeTrustPercentageofadultsworldwidewhoreportedbeingmoredepressedduetotheCOVID-19pandemicasofJune2020,byageDepressionlevelincreasesduringtheCOVID-19pandemicworldwideJune2020,byageNomoredepressedthanbefore80.1%Moredepressed85.2%90%80%70%60%50%40%30%20%10%0%81.5%80.8%77.9%73.5%65.2%34.8%26.5%22.1%19.9%19.2%18.5%14.8%18to24years25to34years35to44years45to54years55to64years65to74years75yearsandolder7Description:AsurveyfromJune2020,foundthataround34.8percentofadultsaged18to24yearsreportedbeingmoredepressedduetotheCOVID-19pandemic.ThisstatisticillustratesthepercentageofadultsworldwidewhoreportedbeingmoredepressionduetotheCOVID-19pandemicasofJune2020,byage.ReadmoreNote(s):Worldwide;June17to22,2020;69,047respondents;18yearsandolder;22countriesSource(s):SleepCycleShareofrespondentswhoreportedsufferingfromamentalhealthconditioninselectedEuropeancountriesasof2020PrevalenceofmentalhealthillnessesinEuropein2020,byselectedcountrySufferfromatleastonementalhealthconditionAnxietydisorderDepressionSomethingelse35%30%25%20%15%10%5%30%27%27%25%25%24%17%22%14%21%20%20%17%15%15%14%11%13%10%10%9%9%8%7%7%6%6%6%

6%6%3%3%0%UnitedKingdomFranceSwedenGermanyPolandItalySpainDenmark8Description:InNovember2020,asurveyfoundthat21percentofFrenchrespondentsreportedtobesufferingfromananxietydisorder,thehighestshareamongtheshowncountries.IntheUK,30percentofrespondentsoverallreportedthattheysufferedfromatleastonementalhealthillness.ReadmoreNote(s):EuropeSource(s):YouGovCHAPTER

02DepressionamongthegeneralpopulationPercentageofindividualsreportingsymptomsofdepressioninItalyfrom2008to2022ShareofindividualsreportingdepressionsymptomsinItaly2008-20228.0%7.8%7.5%7.0%6.5%6.0%5.5%5.0%6.9%6.8%6.7%6.5%6.4%6.4%6.3%6.3%6.2%6.2%6%6%5.9%20195.6%2016200820092010201120122013201420152017201820202021202210Description:Between2008and2022,theshareofindividualsreportingdepressionsymptomsinItalyfluctuated.Thehighestsharewasrecordedin2008,when7.8percentofrespondentsdeclaredhavingexperiencedsuchsymptomsinthetwoweeksprecedingthesurvey.Conversely,in2016,just5.6percentofadultsinItalysufferedfromdepression.In2021and2022,respondentswhoexperienceddepressionsymptomstotaled6.2percent.Thisfigureshowstheshareofindividualsreportingdepression[...]

ReadmoreNote(s):Italy;2008to2022;18-69yearsSource(s):IstitutoSuperiorediSanitàPercentageofindividualsreportingsymptomsofdepressioninItalybetween2021and2022,byagegroupShareofindividualsreportingdepressionsymptomsinItaly2021-2022,byage8%7.2%7%6%6%5%4%3%2%1%0%5.5%18-34years35-49years50-69years11Description:Accordingtothedata,between2021and2022,thepercentageofindividualsreportingsymptomsofdepressioninItalywasthehighestamongindividualsagedbetween50and69years,with7.2percent.ThisfigureshowstheshareofindividualsreportingdepressionsymptomsinItalybetween2021and2022,byagegroup.ReadmoreNote(s):Italy;2021and2022;18-69yearsSource(s):IstitutoSuperiorediSanitàPercentageofindividualsreportingsymptomsofdepressioninItalybetween2021and2022,bygenderShareofindividualsreportingdepressionsymptomsinItaly2021-2022,bygender9%8.2%8%7%6%5%4%3%2%1%4.5%0%WomenMen12Description:Accordingtothedata,thepercentageofindividualsreportingsymptomsofdepressioninItalywasthehighestamongwomen,with8.2percentbetween2021and2022.Conversely,4.5percentofmenhaddepressionsymptomsduringthesameperiod.ThisfigureshowstheshareofindividualsreportingdepressionsymptomsinItalybetween2021and2022,bygender.ReadmoreNote(s):Italy;2021and2022;18-69yearsSource(s):IstitutoSuperiorediSanitàPercentageofindividualsreportingsymptomsofdepressioninItalybetween2021and2022,byeconomicstatusShareofindividualswithdepressionsymptomsinItaly2021-2022,byeconomicstatus20%17.4%18%16%14%12%10%8%7.7%6%4.4%4%2%0%ManyeconomicproblemsFeweconomicproblemsNone13Description:Accordingtothedata,mostindividualsreportingsymptomsofdepressioninItalywerealsofacingeconomicproblems.Between2021and2022,around17.4percentofindividualswithmanyeconomicproblemsweredepressed.ThisfigureshowstheshareofindividualsreportingdepressionsymptomsinItalybetween2021and2022,byeconomicstatus.ReadmoreNote(s):Italy;2021and2022;18-69yearsSource(s):IstitutoSuperiorediSanitàPercentageofindividualsreportingsymptomsofdepressioninItalybetween2021and2022,byregionShareofindividualsreportingdepressionsymptomsinItaly2021-2022,byregionShareofindividuals6%0%2%4%8%10%12%14%SardiniaMolise11.7%10.3%Marche9.1%Umbria8.1%7.9%Emilia-RomagnaPiedmontLiguria7.4%6.9%6.9%AostaValleyBasilicataSicily6.6%6.5%6.2%AbruzzoVenetoLazio6.2%6.2%14Description:Between2021and2022,about6.4percentofindividualsinItalyexperienceddepressionsymptoms.Accordingtothedata,Sardiniawastheregionwiththelargestshareofthepopulationaged18-69yearsdeclaringtohavesufferedfromdepressionsymptomsduringthetwoweeksprecedingtheinterview,amountingtoalmost12percent.Conversely,just3.1percentofindividualsresidingintheAutonomousProvinceofBolzanoreportedsufferingfromdepressivesymptomsduringthis[...]

ReadmoreNote(s):Italy;2021-2022;18-69yearsSource(s):IstitutoSuperiorediSanitàPercentageofdepressedindividualsaskingforhelpinItalyin2021-2022,byregionShareofdepressedpeopleseekinghelpinItaly2021-2022Shareofrespondents30%

40%0%10%20%50%60%70%80%90%AutonomousProvinceofBolzano84%AutonomousProvinceofTrento76.7%LiguriaCalabria76.1%75.6%Apulia74.2%Sardinia74%Veneto73.8%Friuli-VeneziaGiuliaLombardy*Umbria72.8%72.3%72.2%TuscanyPiedmontItaly65.1%62.8%62.4%15Description:Asof2022,about6.2percentofadultsinItalyreporteddepressionsymptoms.Amongthem,onaverage62.4percentaskedforhelptogetoutofthismentalstatebetween2021and2022.Accordingtothedata,theregionswherepeoplesufferingfromdepressionwereleastlikelytoseekhelpwereSicilyandMolise.TheAutonomousProvinceofBolzanoandTrento,onthecontrary,weretheregionswiththehighestpercentageofindividualsdeclaringtheyreachedoutforhelpwhen[...]

ReadmoreNote(s):Italy;2021to2022;18-69years;*DataforLombardyrefertotheyears2016-2019.Releasedaterepresentsthedatefigureswereaccessed.

ReadmoreSource(s):IstitutoSuperiorediSanitàCHAPTER

03DepressionamongelderlyPercentageofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,byagegroupShareofelderlyindividualsreportingdepressionsymptomsinItaly2021-2022,byage16%14%12%13.6%10.7%10%8%6%4%2%0%8.3%65-74years75-84years85yearsandabove17Description:Accordingtothedata,between2021and2022,theshareofelderlyindividualsreportingdepressionsymptomsinItalywasthehighestamongpeopleaged85yearsandabove.ThisstatisticshowstheshareofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,byagegroup.ReadmoreNote(s):Italy;2021and2022;65yearsandolderSource(s):IstitutoSuperiorediSanitàPercentageofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,bygenderElderlyindividualsreportingdepressionsymptomsinItaly2021-2022,bygender14%12.8%12%10%8%5.7%6%4%2%0%WomenMen18Description:Accordingtothedata,between2021and2022,theshareofelderlywomensufferingfromdepressionsymptomsinItalymorethandoubledtheshareofelderlymen.ThisstatisticshowstheshareofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,bygender.ReadmoreNote(s):Italy;2021and2022;65yearsandolderSource(s):IstitutoSuperiorediSanitàPercentageofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,byeconomicstatusElderlyreportingdepressionsymptomsinItalyin2021-2022,byeconomicstatus35%30.2%30%25%20%15%12.6%10%5%5.9%0%ManyeconomicproblemsFeweconomicproblemsNone19Description:Accordingtothedata,mostofelderlypeoplereportingdepressionsymptomsinItalywerealsofacingmanyeconomicproblems.Between2021and2022,around30.2percentofelderlyindividualshavingmanyeconomicproblemsweredepressed.ThisstatisticshowstheshareofelderlyindividualsexperiencingsymptomsofdepressioninItalybetween2021and2022,byeconomicstatus.ReadmoreNote(s):Italy;2021and2022;65yearsandolderSource(s):IstitutoSuperiorediSanitàPercentageofelderlyindividualsexperiencingdepressionsymptomsinItalybetween2021and2022,byregionShareofelderlyreportingdepressionsymptomsinItaly2021-2022,byregionShareofindividuals6%

8%0%2%4%10%12%14%16%18%UmbriaLiguriaBasilicataSardinia16.7%14.3%13.9%13.3%SicilyLazio12.2%11.9%MoliseFriuli-VeneziaGiuliaVeneto10.2%10%10%Abruzzo9.3%8.9%CampaniaEmilia-RomagnaMarche8.1%7.4%20Description:Between2021and2022,about9.5percentofelderlyindividualsinItalyexperienceddepressionsymptoms.Accordingtothedata,Umbriawastheregionwiththelargestshareofpopulationaged65yearsandolderdeclaringtohavingsufferedfromdepressionsymptomsduringthetwoweeksprecedingtheinterview,amountingto16.7percent.Conversely,just3.5percentofelderlyresidingintheregionofTuscanysufferedfromdepressivesymptomsduringthisperiod.Thisstatisticshows[...]

ReadmoreNote(s):Italy;2021-2022;65yearsandolderSource(s):IstitutoSuperiorediSanitàCHAPTER

04ConsumptionofantidepressantsPrevalenceofantidepressantconsumptioninItalyin2021,bygenderPrevalenceofantidepressantuseinItalyin2021,bygender40%35%30%25%20%15%10%5%33.5%30.9%25.6%0%MenWomenTotal22Description:Accordingtothedata,inItaly,almost31percentofpatientswithadiagnosisofdepressionusedantidepressantsin2021.Womendiagnosedwithdepressionhadahigherprevalenceofantidepressantusecomparedtomen.ThisstatisticshowstheprevalenceofantidepressantconsumptioninItalyin2021,bygender.ReadmoreNote(s):Italy;2021Source(s):AgenziaItalianadelFarmacoPrevalenceofantidepressantconsumptioninItalyin2021,byagegroupPrevalenceofantidepressantuseinItalyin2021,byage50%46.2%45.6%45%40%35%30%25%20%15%10%5%36.1%30.9%26%16.8%0%≤45years46-65years66-74years75-84years≥85Total23Description:Accordingtothedata,inItaly,almost31percentofpatientswithadiagnosisofdepressionusedantidepressantsin2021.Patientsagedabove85yearsweretheoneswiththehighestconsumptionofantidepressantsafteradiagnosisofdepression,with46.2percent.ThisstatisticshowstheprevalenceofantidepressantuseinItalyin2021,byagegroup.ReadmoreNote(s):Italy;2021Source(s):AgenziaItalianadelFarmacoPrevalenceofantidepressantconsumptioninItalyin2021,bygeographicareaPrevalenceofantidepressantuseinItalyin2021,bygeographicarea40%34.9%35%30%25%20%15%10%5%32.3%30.9%27.2%0%NorthCenterSouthandIslandsTotal24Description:Accordingtothedata,inItaly,almost31percentofpatientswithadiagnosisofdepressionusedantidepressantsin2021.Inthenorthofthecountry,32.3percentofpatientsdiagnosedwithdepressionusedantidepressants.ThisstatisticshowstheprevalenceofantidepressantuseinItalyin2021,bygeographicalarea.ReadmoreNote(s):Italy;2021Source(s):AgenziaItalianadelFarmacoConsumptionrateofantidepressantsinItalyfrom2013to2022(inDDDper1,000inhabitantsperday)ConsumptionofantidepressantsinItaly2013-202247.046.045.044.043.042.041.045.844.643.642.841.640.439.740.039.038.039.539.239201320142015201620172018201920202021202225Description:Between2013and2022,consumptionofantidepressantdrugsincreasedinItaly.Accordingtothedata,infact,in2013about39DDDs(dailydefineddoses)wereconsumedper1,000inhabitantsperday.By2022,theconsumptionofantidepressantreached45.8DDDsper1,000inhabitantsperday.ThisfigureshowstheconsumptionrateofantidepressantsinItalyfrom2013to2022(inDDDper1,000inhabitantsperday).

ReadmoreNote(s):Italy;2013to2022Source(s):AgenziaItalianadelFarmacoLevelofconsumptionofantidepressantsinItalyin2022,byactiveingredient(inDDDper1,000inhabitantsperday)ConsumptionrateofantidepressantsinItalyin2022,byactiveingredientConsumptionrateinDDDper1,000inhabitantsperday01234567891011SertralineParoxetineEscitalopramCitalopramVenlafaxineDuloxetineVortioxetineMirtazapineTrazodoneBupropion9.88.27.74.13.93.421.91.40.326Description:TheconsumptionofantidepressantsinItalyreached45.8dailydefineddoses(DDD)per1,000inhabitantsperdayin2022.Thisstatisticbreaksdownthisfigurebyactiveingredient.Accordingtothedata,Sertralinewasthemostconsumeddrugintheclassofantidepressants,withaconsumptionrateof9.8DDDper1,000inhabitantsperday.Paroxetinefollowedwith8.2dailydefineddosesconsumedper1,000inhabitants.ThisstatisticshowstheconsumptionofantidepressantsinItalyin[...]

ReadmoreNote(s):Italy;2022Source(s):AgenziaItalianadelFarmacoConsumptionofantidepressantsinItalyin2022,bygeographicarea(inDDDper1,000inhabitants)ConsumptionofantidepressantsinItalyin2022,byarea6051.348.55040302010045.838.5NorthCenterSounthandIslandsItaly27Description:Accordingtothedata,theconsumptionofantidepressantsinItalyamountedto45.8dailydefineddoses(DDD)per1,000inhabitantsperdayin2022.Southernregionsandislandshadthelowestconsumptionrate,with38.5DDDper1,000inhabitants.ThisstatisticshowstheconsumptionofantidepressantsinItalyin2022,bygeographicarea(inDDDper1,000inhabitantsperday).ReadmoreNote(s):Italy;2022Source(s):AgenziaItalianadelFarmacoConsumptionrateofantidepressantsinItalyin2022,byregion(inDDDper1,000inhabitantsperday)ConsumptionrateofantidepressantsinItaly2022,byregionConsumptionrateinDDDper1,000inhabitantsperday20

30

4001050607080Tuscany67.6Liguria60.3AutonomousProvinceofBolzano5957.857.1UmbriaEmiliaRomagnaPiedmont52.5SardiniaMarche49.447.5AutonomousProvinceofTrento4645.845ItalyAbruzzoAostaValleyVeneto44.944.428Description:In2022,theaveragelevelofconsumptionofantidepressantsinItalywasequalto45.8DDD(dailydefineddose)per1,000inhabitantsperday.Thisfigure,however,variedconsiderablyacrossregions.Accordingtothedata,Tuscanywastheregionwiththehighestantidepressantsconsumptionrate,with67.6DDDper1,000inhabitantsperday.Conversely,just35.8DDDper1,000inhabitantswereconsumeddailyinBasilicata.Thisstatisticdisplaystheconsumptionrateofantidepressantsin[...]

ReadmoreNote(s):Italy;2022Source(s):AgenziaItalianadelFarmacoCHAPTER

05CostandexpenditureofantidepressantsAveragecostofantidepressantsinItalyfrom2014to2022(ineurosperDDD)CostofantidepressantsinItaly2014-20220.60.530.50.50.50.50.50.40.40.40.40.40.460.420.420.420.420.420.410.4120142015201620172018201920202021202230/statistics/1322658/average-cost-of-antidepressants-in-italyAccordingtothedata,since2018,theaveragecostofantidepre